OPEN ARCHITECTURE OF ARCHAEA MCM AND DSDNA COMPLEXES RESOLVED USING MONODISPERSED STREPTAVIDIN AFFINITY CRYOEM

Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

Abstract The cryo-electron microscopy (cryoEM) method has enabled high-resolution structure determination of numerous biomolecules and complexes.Nevertheless, cryoEM sample preparation of challenging Hockey Accessories - Home Sharpening - Consumables proteins and complexes, especially those with low abundance or with preferential orientation, remai

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Amplifying colorectal cancer progression: impact of a PDIA4/SP1 positive feedback loop by circPDIA4 sponging miR-9-5p

Objective: Colorectal cancer (CRC) is a prevalent malignant tumor with a high fatality rate.CircPDIA4 has been shown to have a vital role in cancer development by acting as a facilitator.Nevertheless, the impact of the circPDIA4/miR-9-5p/SP1 axis on development of CRC has not been studied.Methods: Western blot, immunohistochemistry, and reverse tra

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